Opening. Surveillance, Spectrum, and Burden of Tick-Borne Diseases

8:00 am Introduction
Lonnie King, D.V.M., M.S., M.A.
Chair, Committee on Lyme Disease and Other Tick-Borne Diseases
Dean, College of Veterinary Medicine
The Ohio State University

8:15 am A Systems Approach in Understanding Tick-Borne Diseases: People, Animals, and the Ecosystem
Richard Ostfeld, Ph.D. (confirmed) Disease Ecologist
Cary Institute of Ecosystem Studies

SURVEILLANCE, SPECTRUM, AND BURDEN OF TICK-BORNE DISEASES

9:00 am Moderator: Gordon Schutze, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Professor and Vice-Chairman for Educational Affairs
Department of Pediatrics
Vice President, Baylor International Pediatric AIDS Initiative
Baylor College of Medicine
Texas Children's Hospital

9:05 am Landscape of Lyme Disease: Current Knowledge, Gaps, and Research Needs
Gary P. Wormser, M. D. (confirmed)
Professor of Medicine
Chief, Division of Infectious Diseases
Vice-Chairman, Department of Medicine
New York Medical College

9:30 am Spectrum of Lyme Disease: Approaches to Understanding Multi-factorial and Multidimensional Diseases
Benjamin J. Luft, M.D. (confirmed)
Edmund D. Pellegrino Professor
Division of Infectious Diseases
State University of New York at Stony Brook

9:45 am Discussion

Surveillance, Spectrum, and Burden of Tick-Gorne Diseases, Part 2

10:20 am Recent Understanding of Babesiosis: Clinical Manifestation, Co-infection, and Research Needs
Peter Krause, M.D. (confirmed)
Senior Research Scientist
Lecturer in Epidemiology, Microbial Diseases
Yale School of Public Health

10:40 am Insights into Ehrlichia & Anaplasma: Surveillance, Co-infection, and Research Needs
J. Stephen Dumler, M.D. (confirmed)
Professor, Department of Pathology
Division of Medical Microbiology
Johns Hopkins University School of Medicine

11:00 am Rickettsia Diseases: Spectrum of Disease, Spatial Clustering, At-Risk Populations, and Research Needs
Jennifer McQuiston, D.V.M, M.S. (confirmed)
National Center for Preparedness, Detection, and Control of Infectious Diseases
Centers for Disease Control and Prevention

11:20 am Discussion

11:40 am Panel: Disease Surveillance & Co-infection
Stephen Dumler, Peter Krause, Benjamin Luft, Jennifer McQuiston, and Gary Wormser

12:15 pm Summation: Unifying Knowledge Gaps and Needs
Gordon Schutze

At-Risk Populations and Human Face of Tick-Borne Diseases

1:10 pm Moderator: Lonnie King

1:15 pm Panel: Genetic and Acquired Determinants of Host Susceptibility and Vulnerable Populations
David Weber, M.D. (confirmed)
Professor of Medicine and Pediatrics, School of Medicine
Professor of Epidemiology, School of Public Health
University of North Carolina
Peter Krause, M.D. (confirmed)
Senior Research Scientist
Lecturer in Epidemiology Microbial Diseases
Yale School of Public Health

1:40 pm Discussion

1:55 pm The Human Face of Tick-Borne Disease Infections
Pamela Weintraub (confirmed)
Author, Cure Unknown
Editor, Discover Magazine


2:15 pm Discussion

Diagnostics and Diagnosis

3:05 pm Moderators: Lynn Gerber, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Director, Center for the Study of Chronic Illness and Disability
College of Health and Human Services
George Mason University
David H. Walker, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Professor and Chair
Department of Pathology
University of Texas Medical Branch at Galveston

3:10 pm Diagnostics for Lyme Disease: Knowledge Gaps and Needs
Maria Aguero-Rosenfeld, M.D. (confirmed)
Professor of Pathology
Director of Clinical Pathology and Microbiology Laboratory
Bellevue Hospital Center


3:30 pm Improved Diagnostics & Novel Approaches to Tick-Borne Disease Infections
Juan Olano, M.D. (confirmed)
Associate Professor, Department of Pathology
Director, Residency Training Program


3:50 pm Potential Bio-Marker Applications for Lyme Disease: Aligning Multiple Symptoms with Biological Measures
Afton Hassett, Psy.D. (confirmed)
Associate Research Scientist, Department of Anesthesiology
Chronic Pain & Fatigue Research Center
University of Michigan Medical School

4:10 pm Discussion

Diagnostics and Diagnosis Part 2

4:40 pm Panel: Challenges for Clinicians in Diagnosis and Management of Chronic Illness
Manifestations: Knowledge Gaps
Sam T. Donta, M.D. (confirmed)
Infectious Disease Specialist
Falmouth Hospital, Massachusetts
Brian Fallon, M.D., M.P.H. (confirmed)
Director of the Center for Neuroinflammatory Disorders and Biobehavioral Medicine
Director of the Lyme and Tick-Borne Diseases Research Center
Columbia University Medical Center
Matthew Liang, M.D., M.P.H. (confirmed)
Professor, Department of Health Policy and Management Harvard School of Public Health Richard F. Jacobs, M.D., F.A.A.P. (confirmed) Robert H. Fiser, Jr., M.D. Endowed Chair in Pediatrics
Chairman, Department of Pediatrics
University of Arkansas for Medical Sciences
President, Arkansas Children's Hospital Research Institute

5:20 pm Discussion

5:45 pm Summation
Lynn Gerber and David Walker

EMERGING INFECTIONS, TICK BIOLOGY, AND HOST-VECTOR INTERACTIONS

8:00 am Introduction
Lonnie King

Moderator: Lonnie King

8:05 am Emerging and Re-Emerging Tick-Borne Infections
Ulrike Munderloh, D.V.M, Ph.D. Associate Professor, Department of Entomology University of Minnesota

8:25 am Natural History of Ticks: Evolution, Adaptation and Biology
Tom G. Schwan, Ph.D., M.S. Chief, Laboratory of Zoonotic Pathogens Chief, Medical Entomology Section National Institute of Allergy and Infectious Diseases

8:45 am Wildlife and Domestic Hosts: Their Roles in Maintaining, Amplifying Pathogens, and their Changing Dynamics
Howard Ginsberg, Ph.D. Research Ecologist United States Geological Survey Professor in Residence, Department of Plant Science University of Rhode Island

9:05 am Discussion

9:20 am Comparative Medical Importance of a One Health Approach to Emerging Tick-borne Diseases
Edward Breitschwerdt, D.V.M. Professor of Internal Medicine College of Veterinary Medicine North Carolina State University Adjunct Professor of Medicine Duke University Medical Center

9:40 am Variation of Borrelia Subspecies: Implications for Human Disease
James H. Oliver, Jr., Ph.D. Director, Institute of Arthropodology and Parasitology Callaway Professor of Biology Georgia Southern University

10:00 am Discussion

PATHOGENESIS -Part 1

10:30 am Moderator: Guy Palmer, D.V.M., Ph.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases Regents Professor of Pathology and Infectious Diseases The Creighton Chair and Director, School for Global Animal Health Washington State University

10:35 am Pathogenesis of Borrelia burgdorferi Infection and Disease
Janis Weis, Ph.D. Professor of Pathology, Department of Pathology University of Utah

10:55 am Duration of Spirochete Infection Following Antibiotic Treatment in Animals
Linda Bockenstedt, M.D. Harold W. Jockers Professor of Medicine Department of Rheumatology Yale School of Medicine

11:15 am Discussion

11:30 am Antigenic Variation as a Mechanism for Persistent Borrelia Infection
Steven Norris, Ph.D. Greer Professor Vice Chair for Research Pathology & Laboratory Medicine University of Texas, Houston

11:50 am Sequestration as a Mechanism for Persistent Borrelia Infection
Stephen Barthold, D.V.M., Ph.D. Distinguished Professor Department of Pathology, Microbiology and Immunology Center of Comparative Medicine School of Veterinary Medicine University of California, Davis

12:10 pm Discussion

PATHOGENESIS -Part 2

1:15 pm Pathogenesis of Ehrlichia and Anaplasma Infection and Disease
Nahed Ismail, M.D., M.Sc., Ph.D., S.M. (ASCP), D. (ABMM) Associate Professor, Department of Pathology Meharry Medical College

1:35 pm Pathogenesis of Rickettsia Infection and Disease
Gustavo Valbuena, M.D. Instructor, Department of Pathology University of Texas Medical Branch

1:55 pm Discussion

2:15 pm Summation
Guy Palmer

SCIENCE, SOCIETY, AND DISEASE

2:20 pm Moderator: Lynn Gerber

2:25 pm The Social Construction of Lyme Disease
Robert Aronowitz, M.D. Professor, Department of History and Sociology of Science University of Pennsylvania

2:45 pm Discussion

PREVENTION

3:05 pm Moderator: Stephen M. Ostroff, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases Director, Bureau of Epidemiology Pennsylvania Department of Health

3:10 pm Current Vaccines for Tick-Borne Disease Infections and Vaccine Development
Jere McBride, Ph.D., M.S. Associate Professor, Department of Pathology University of Texas Medical Branch

3:30 pm Developing Opportunities for Future Vaccines
Wendy Brown, Ph.D., M.P.H. Regents Professor, Department of Veterinary Microbiology and Pathology Washington State University

3:50 pm Discussion

4:10 pm Education, Behavior Change, and Other Non-Pharmaceutical Measures Against Lyme and Other Tick-Borne Diseases
Paul Mead, M.D., M.P.H. Medical Epidemiologist, Division of Vector-Borne Infectious Diseases National Center for Infectious Diseases Center for Disease Control and Prevention

4:30 pm Vector- and Host-Targeted Strategies for Prevention of Tick-Borne Diseases
José M.C. Ribeiro, M.D., Ph.D. Chief, Vector Biology Section Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases

4:50 pm Discussion

5:10 pm Summation
Steve Ostroff

CLOSING

5:20 pm Moderator: Lonnie King

5:25 pm Panel: State of Science, General Research Gaps and Opportunities in Tick-Borne Diseases
John Aucott, M.D. Founder, Lyme Disease Research Foundation of Maryland Physician, Park Medical Associates
Linda Bockenstedt, M.D. Harold W. Jockers Professor of Medicine Department of Rheumatology Yale School of Medicine
J. Stephen Dumler, M.D. Professor, Department of Pathology Division of Medical Microbiology Johns Hopkins University School of Medicine
Susan O’Connell, M.D. Consultant Microbiologist Head of the Lyme Borreliosis Unit Southampton General Hospital
Gregg P. Skall, J.D. Counsel, National Capital Lyme and Tick-borne Disease Association Member, Womble Carlyle Sandridge & Rice, PLLC

5:55 pm Discussion

6:25 pm Final Summation and Closing Remarks
Lonnie King