AGENDA
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8:15 am
Welcome and introduction to the Ninth Annual Beebe Symposium
(15 minutes)

8:30 am
Background on radiation exposure in medical, occupational, and environment settings (20 minutes)

8:50 am
Questions and discussion (10 minutes)

Session 1: Scientific Advances in Low-Dose Radiation Biology

Topics: mechanisms of response at low doses, including adaptive response and homeostasis; linearity/non-linearity of response at low doses; role of genetics and epigenetics; measurement challenges at cellular and molecular levels. Response of animal organ systems to low dose/low dose rate radiation, early and late effects, cancer and non-cancer effects.

9:00 am
Speaker 1: Cellular (30 minutes)
William F. Morgan, Pacific Northwest National Laboratory

9:30 am
Speaker 2: Systems (30 minutes)
Mary Helen Barcellos-Hoff, NYU Medical Center

10:00 am
Questions/discussion (15 minutes)

10:15 am Break (20 minutes)

Session 2: Scientific Advances in Low-Dose Radiation Epidemiology

Topics: Exposure measurement and modeling approaches; linearity/nonlinearity in epidemiologic cohorts; gaps in knowledge and methodology

10:35 am
Speaker 1: RERF (30 minutes)
Roy Shore, Radiation Effects Research Foundation

11:05 am
Speaker 2: Other low-dose cohorts (30 minutes)
Ethel Gilbert, National Cancer Institute

11:35 am
Questions/discussion (15 minutes)

Session 3: Panel Discussion

11:50 am
Discussion of key points from this morning's session to include how
data from epidemiology and from radiobiology studies can synergize.
(Speakers will be the panelists) (25 minutes)

12:15 pm
Lunch (3rd floor refectory)

Session 4: Translating Radiation Biology and Epidemiology into Risk Estimates

1:30 pm
Low-dose risk estimation (30 minutes)
Julian Preston, Environmental Protection Agency

2:00 pm
Questions/discussion (15 minutes)

Session 5: Using Low-Dose Radiation Biology and Epidemiology in Decision
Making: Case Studies

2:15 pm
Case Study 1: Setting a national action level for radon (20 minutes)
Paul Locke, Johns Hopkins School of Public Health

2:45 pm
Questions/discussion (15 minutes)

2:55 pm
Break (20 minutes)

3:15 pm
Case Study 2: Establishing "Safe" or "Acceptable" levels for diagnostic
radiation use (CT) (20 minutes)
David Hoel, Medical University of South Carolina

3:45 pm
Questions/discussion (10 minutes)

3:55 pm
Case Study 3: Setting radiation protection standards for civilian nuclear
facilities (20 minutes)
Ralph Andersen, Nuclear Energy Institute

4:25 pm
Questions/discussion

Session 6: Panel Discussion and Closing Remarks

4:35 pm
Discussion of key points from this afternoon's sessions
(Speakers will be the panelists) (25 minutes)

5:00 pm
Closing remarks (15 minutes)

5:15 pm
Adjourn